The Microscopic Minute 

a Pocket Pathologist Blog
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Paraneoplastic HyperCa is a Common Problem with AGASACA

Did you know that paraneoplastic hypercalcemia is associated with 27-90% of anal sac adenocarcinoma cases, which may result in renal disease?

This is kind of a big-ish range of reported incidence of...

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It's finally easy to take microscopic photos with your phone

One of the things I hear all the time from vets and vet techs is, "How do I take better microscopic photos with my phone?".


Usually, I respond with some tips on how to hold the phone steady,...

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What's Inside a Normal Anal Sac?

The anal sacs are weird little thin-lined pouches which produce the stank nasty secretions we all know and hate.

But what exactly is inside the anal sacs normally?

If you take a look at anal sac...

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A Tale of Two Epithelial Cells

I love this photo because the vet got lucky and picked up two types of epithelial cells in one aspirate!

This was a dog with a large mass protruding from the perianal area which was aspirated...


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Ring Around the Roseys in Anal Sac Adenocarcinoma

Pseudoacinar structures (aka rosettes) are a type of cell pattern you may see in neuroendocrine (and neuroendocrine-like) neoplasms where the epithelial cells and their nuclei form little circles.


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Inflammatory Macrophages and Their Many Hats

Macrophages have to be one of the most obnoxious cells in cytology. I mean, don’t get me wrong, I’m grateful for them….they do a bajillion different things and are super...

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