The Microscopic Minute 

a Pocket Pathologist Blog
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A Cytologic Spin on Vax Adjuvant

Adjuvant often appears like this globby magenta material on cytology, but interestingly, sometimes vaccine adjuvant can be blue!

There was a study in Vet Clin Path that looked at this and found...

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Vaccine Adjuvant is Gorg on Cytology

This month’s case highlight is from Kari Cameron! This a beautiful example of a vaccine hypersensitivity reaction in a 10 mo Yorkie. This pup was vaccinated 2 weeks prior and presented...

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Definition Time! Let's Talk About the N:C Ratio

Definition time!

The N:C (nuclear to cytoplasmic) ratio is a term used to describe how much cytoplasm there is in a cell compared to how big or small the nucleus is.


Cells with a high...

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Don't Forget about These Cells that Might Show Up in Organ Aspirates

It’s super important to recognize what mesothelial cells look like, because they can be easily mistaken for neoplastic epithelial cells if you’re not expecting them.

This is one way...

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These Cells Shouldn't be in a Liver!

What are those eosinophils doing in there?

This was a liver aspirate from a dog with an enlarged liver.  There are tons of intermediate to large sized lymphocytes (not supposed to be in a...

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Hey Hepatocytes...You're Showing Your Age...

Definition time!

Lipofuscin is a neat little pigment that you can find in the cytoplasm of hepatocytes. It’s just a normal aging change, so no need to panic when you see it.

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